The obnoxious drunks edition of Awards Show, with Brad and Wayne presenting to winners Ryan and Colin; Brad and Wayne sing a swing Duet to special guests Hugh, Victoria, and Ava; Scenes from a Hat are "Superman's secret inner thoughts", "things you did as a child that aren't as cute now that you're an adult", "if celebrities had been the first people to walk on the moon", and "inappropriate slide shows that your neighbors make you sit through"; Ryan and Colin play Living Scenery with Ava and Victoria as props, and the guys play two treasure hunters canoeing down the Amazon who pitch a tent by the river and get attacked by natives.
Colin wins, so it's Brad and Wayne against Ryan and Drew in Props.

Paige discovers that a 11-year-old runaway is a Firestarter, and takes him home so that the Charmed Ones can keep him safe. The sisters discover that his foster parents are demons, and plans to raise the child to be evil. Elsewhere, Cole proposes to Phoebe using her grandmother's ring, but the trinket carries an odd curse.

Chandler is dying to know what is inside Monica's secret closet. Joey suggests Rachel to move in with Ross because he always misses out.

Catherine is ordered by a kidnapper to accompany a man who is to deliver $1 million in ransom to him or else he will kill the man's mistress. But when the million is paid, they learn that his mistress is already dead.

Lois runs into an ex-boyfriend while shopping. Knowing Peter would be jealous, she has coffee with him behind Peter's back. Peter, while hanging with the guys in Joe's new police surveillance van, spot Lois. Angered, Peter tries to make Lois jealous by having prostitutes pose as his old girlfriends. After a marriage therapist suggesting a trial separation, Quagmire makes his move on Lois, and Peter goes on his own date... with actress Jennifer Love Hewitt. Meanwhile, Stewie and Brian become superglued together, and must deal with each other waiting for the solvent to arrive, and actually warm up to one another.

When Grace is invited to her ex-fianc?'s wedding, she hauls along a reluctant Will just to convey a false air of success -- but when she denigrates the bridegroom's faults at the rehearsal dinner, she's confronted by a weeping bride-to-be who now wants to flee. Meanwhile, Elliot's fuming mother gets in Jack's face when he allows Elliot to frost his hair and demands that he never see his son again. In addition, Will poses as a swinging tennis pro until he meets his match.

Eleanor Carter tends to a young leukemia patient, trying to make up for Bobby's death many years ago. Mark treats the victims of a letter bomb, and later treats his own daughter when Ella is rushed in after swallowing some of Rachel's Ecstasy. Abby treats a young girl who has been chauffering her drunken mother around. Abby also hides Joyce in her apartment while Brian searches for her and causes a ruckus. An allergic Gallant treats a blind man with a dog. Chen returns to the day shift, working with Weaver for the first time. Romano gives some of Weaver's duties to Lewis, making Kerry mad, until she meets a new friend on her way home.

Tonight, actor Jason Schwartzman promotes his new movie Slackers.

It's the 2nd of the Extreme Annihalators. 6 robots go in and only one will be the champion.